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Mequitazine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mequitazine图片
CAS NO:29216-28-2
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Primalan
LM-209
美喹他嗪
Metaplexan
Virginan
产品介绍
Mequitazine 是一种有效的、非镇静剂和长效组胺 H1 拮抗剂。

产品描述

Mequitazine is an effective, nonsedative and long-acting histamine H1 antagonist.

体外活性

Mequitazine is widely studied and used for allergic disorders such as hay fever and urticaria[1]. Mequitazine demonstrates significant bactericidal effects against all the tested clinical isolates including Ps. aeruginosa. Its effect against the Gram-positive isolates is more pronounced [2].

体内活性

Mequitazine antagonizes the effect of histamine in guinea-pig ileum competitively. Mequitazine at 107 produces a parallel shift of the dose-response curve to acetylcholine in the rat duodenum. Mequitazine at highest concentration shows anticholinergic activity [3]. Mequitazine inhibits contractile responses to KCl, phenylephrine (PE), 5-hydroxytryptamine (5-HT), and Ca2+ in rat aorta [4].

Cas No.

29216-28-2

分子式

C20H22N2S

分子量

322.47

别名

Primalan;LM-209;美喹他嗪;Metaplexan;Virginan

储存和溶解度

DMSO:15 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years