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(±)-Stylopine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
(±)-Stylopine图片
CAS NO:4312-32-7
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
四氢黄连碱
(-)-STYLOPINE
产品介绍
(-)-STYLOPINE 是一种生物碱类化合物,分离自紫堇属之植物块茎,具有抗寄生虫及抗炎作用。

产品描述

(-)-STYLOPINE is a natural product from Chelidonium majus L

体外活性

Stylopine per se concentration-dependently reduced nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-a (TNF-ɑ) and interleukin-ll3 (IL-1β), and the IL-6 production and cyclooxygenase-2 (COX-2) activity caused by the LPS stimulation. The levels of inducible nitric oxide synthase (iNOS) and COX-2 protein expressions were markedly suppressed by stylopine in a concentration dependent manner. These results suggest that stylopine suppress the NO and PGE2 production in macrophages by inhibiting the iNOS and COX-2 expressions. These biological activities of stylopine may contribute to the anti-inflammatory activity of Cheli- donium majus.

Cas No.

4312-32-7

分子式

C19H17NO4

分子量

323.34

别名

四氢黄连碱;(-)-STYLOPINE

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years