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endo-BCN-O-PNB
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
endo-BCN-O-PNB图片
CAS NO:1263166-91-1
包装与价格：
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
endo-BCN-O-PNB 是一种 PROTAC linker，属于 alkyl/ether 类。可用于合成 PROTAC 分子。
Cas No.1263166-91-1
分子式C17H17NO5
分子量315.32
溶解度DMSO : 100 mg/mL (317.14 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

endo-BCN-O-PNB is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.