Moringin 是一种异硫氰酸酯,由 Moringa oleifera 种子中存在的硫代葡萄糖苷前体 glucoMoringin 通过黑芥子酶介导水解获得。Moringin 具有抗炎和抗氧化特性。
产品描述
Moringin is an isothiocyanate obtained from myrosinase-mediated hydrolysis of the glucosinolate precursor glucoMoringin present in Moringa oleifera seeds. Moringin has anti-inflammatory and antioxidative properties.
体外活性
Moringin modulates neuroinflammation via the β-catenin-PPARγ axis and activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis. Moringin is effective in inducing apoptosis through p53 and Bax activation and Bcl-2 inhibition. Moringin demonstrates the antitumor efficacy in human malignant astrocytoma cells. The combination of Cannabidiol (5μM) and Moringin (5μM) has anti-inflammatory, antioxidative, and anti-apoptotic effects[1].
Cas No.
73255-40-0
分子式
C14H17NO5S
分子量
311.35
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years