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MIR96-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
MIR96-IN-1图片
CAS NO:1311982-88-3
包装与价格:
包装价格(元)
50 mg电议
100 mg电议

产品介绍

产品描述

MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.

体外活性

MIR96-IN-1 inhibits Drosha cleavage of pri-miR-96, as evidenced by an increase in the levels of pri-miR-96 and a reduction in levels of pre- and mature miR-96 in treated cells, as expected if MIR96-IN-1 binds to the Drosha site. MIR96-IN-1 efficiently and selectively silences production of miR-96 at 40 μM while not affecting miR-182 or -183. MIR96-IN-1 inhibits biogenesis of its target precursor miRNA to varying extents: MIR96-IN-1 reduces the expression level of miR-96 by 90% at 40 μM [1].

Cas No.

1311982-88-3

分子式

C33H48N8O2

分子量

588.79

储存和溶解度

DMSO:100 mg/mL (169.84 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years