CCCP 是氧化磷酸化解偶联剂,可诱导 PINK1 激活,促进 Parkin 在 Ser65 位点磷酸化。
产品描述
CCCP inhibits activation of STING and its downstream signalling molecules, TBK1 and IRF3. CCCP inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP).
Cas No.
555-60-2
分子式
C9H5ClN4
分子量
204.62
别名
Carbonyl Cyanide m-Chlorophenylhydrazone;Carbonyl cyanide 3-chlorophenylhydrazone;羰基氰化氯苯腙
储存和溶解度
DMSO:20 mg/mL
Ethanol:5 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years