Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用,可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
产品描述
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhibiting hyperglycemia and oxidative stress. Morroniside can notably protect the brain from damage induced by focal cerebral ischemia which might be related to morroniside antioxidant and anti-apoptotic properties in the brain.
Cas No.
25406-64-8
分子式
C17H26O11
分子量
406.384
别名
莫诺苷;奎宁树
储存和溶解度
Pyridine, Methanol:Soluble
Ethanol:73 mg/mL(179.6 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years