Iron sucROSe 是一种静脉注射铁制剂，也是一种促氧化剂，可用于研究缺铁性贫血。
产品描述
Iron sucrose is treatment of iron deficiency anemia.
体外活性
In vitro conditions iron induces a dose-dependent inhibition of viability of the mesothelial cells as reflected by inhibition of the cells growth by 34% at Fe 0.1 mg mL-1 vs. control (P
细胞实验
in vitro experiments on human peritoneal, the mesothelial effect of elemental iron (in conc. 0.0001-1 mg mL-1) present in Venofer on their viability, growth and synthesis of IL-6 was studied. Additionally we evaluated with a fluorescent probe (2',7'-dichlorodihydro-fluorescein diacatate) generation of reactive oxygen species in cells exposed to iron sucrose. We also measured accumulation of iron in the cytoplasm of mesothelial cells after their in vitro exposure to Venofer[1].
Cas No.
8047-67-4
分子式
C18H24Fe2O24
分子量
736.056
别名
蔗糖铁;Sucroferric oxyhydroxide;Iron saccharate
储存和溶解度
DMSO:100 mg/mL (135.85 mM)
H2O:100 mg/mL (135.85 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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