CD73-IN-3 是一种有效的选择性 CD73 抑制剂,IC50 为 28 nM,具有癌症的研究潜力。详细信息来源于专利 WO2019168744 A1 中的例 2 。
产品描述
LY-3475070 is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
Cas No.
2375815-63-5
分子式
C15H18N4O2
分子量
286.335
别名
EX-A4254;LY-3475070
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years