ZD 7155 hydrochloride is an antagonist of angiotensin II receptor type 1 (AT1 receptor).

ZD 7155 and losartan behave as competitive antagonists and the pressor response curve to angiotensin II is shifted to the right in conscious SD rats. Experiments in conscious SD rats also show that ZD 7155 is approximately ten times as potent as losartan in suppressing the angiotensin II-induced pressor response (240 ng/kg; 10 min infusion).

146709-78-6

C26H27ClN6O

474.99

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years