Levofloxacin hydrochloride 是一种广谱的第三代氟喹诺酮类抗生素，是氧氟沙星的光学活性L-异构体，具有抗菌活性。左氧氟沙星通过细菌细胞壁扩散并通过抑制 DNA 促旋酶（细菌拓扑异构酶 II）起作用，这是一种 DNA 复制、RNA 转录和细菌 DNA 修复所需的酶。 DNA 促旋酶活性的抑制导致细菌细胞生长受阻。

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.

177325-13-2

C18H21ClFN3O4

397.8

DMSO:5 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years