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6-Mercaptopurine hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
6-Mercaptopurine hydrate图片
CAS NO:6112-76-1
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
6-巯基嘌呤(一水合物)
6-Mercaptopurine monohydrate
6-巯基嘌呤 一水合物
6-Mercaptopurine (6-MP) Monohydrate
产品介绍
6-Mercaptopurine hydrate 是一种核苷代谢抑制剂。它通过抑制嘌呤代谢来干扰核酸合成,通常与其他药物联合用于白血病的治疗或缓解维持计划。

产品描述

6-Mercaptopurine anhydrous is a Nucleoside Metabolic Inhibitor. It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.

体外活性

Mercaptopurine is widely used to treat malignancies, rheumatic diseases, dermatologic conditions, inflammatory bowel disease, and solid organ transplant rejection. [1] Mercaptopurine inhibits purine nucleotide synthesis and metabolism by inhibiting an enzyme called Phosphoribosyl pyrophosphate amidotransferase (PRPP Amidotransferase). PRPP Amidotransferase is the rate limiting enzyme of purine synthesis. It alters the synthesis and function of RNA and DNA. Mercaptopurine interferes with nucleotide interconversion and glycoprotein synthesis. [2]

Cas No.

6112-76-1

分子式

C5H6N4OS

分子量

170.19

别名

6-巯基嘌呤(一水合物);6-Mercaptopurine monohydrate;6-巯基嘌呤 一水合物;6-Mercaptopurine (6-MP) Monohydrate

储存和溶解度

H2O:<1 mgml
DMSO:100 mg/mL
Ethanol:<1 mgml
Powder: -20°C for 3 years
In solvent: -80°C for 2 years