Tegafur 是一种前药,在肝脏中被细胞色素 P-450 酶逐渐转化为氟尿嘧啶。它是抗代谢物氟尿嘧啶的同源物,具有抗肿瘤活性。
产品描述
Ftorafur is a congener of the antimetabolite fluorouracil with antineoplastic activity. Ftorafur is a prodrug that is gradually converted to fluorouracil in the liver by the cytochrome P-450 enzyme.
Cas No.
17902-23-7
分子式
C8H9FN2O3
分子量
200.17
别名
FT 207;NSC 148958;替加氟;Fluorafur;FT-207
储存和溶解度
Ethanol:7 mg/mL (34.97 mM)
DMSO:38 mg/mL (189.8 mM)
H2O:8 mg/mL (39.96 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years