Unesbulin 是一种口服有效和选择性的 B 细胞特异性莫洛尼氏鼠白血病病毒整合位点 1 抑制剂。它在急性髓细胞白血病细胞中可下调 MCL-1 并诱导不依赖 p53 的线粒体凋亡，具有抗白血病作用。

PTC596 is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).

1610964-64-1

C19H13F5N6

420.34

PTC596

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years