Nalidixic acid是一种喹诺酮类抗生素，对革兰氏阳性和革兰氏阴性细菌有效。它在较低浓度下有抑菌作用，而在较高浓度下有杀菌作用。它抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基，并可逆地阻止易感细菌中的 DNA 复制。

Nalidixic acid is a synthetic 1, 8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA GYRASE.

389-08-2

C12H12N2O3

232.24

萘啶酸;NSC-82174

H2O:<1 mgml
Ethanol:<1 mgml
DMSO:6 mg/mL (25.83 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years