DHODH-IN-4 是人和 PlaSmodium falciparum 二氢乳清酸脱氢酶 (DHODH) 的抑制剂，其对 PfDHODH 和 HsDHODH 的IC50 值分别为 4 μM 和 0.18 μM。DHODH-IN-4 (compound 17) 具有抗疟疾活性。

DHODH-IN-4 is a human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) inhibitor. The IC50 values of PfDHODH and HsDHODH are 4 μM and 0.18 μM, respectively. DHODH-IN-4 has antimalarial activity.

1148125-93-2

C17H12Cl2N2O2

347.2

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years