NCGC00029283 是一种 werner 综合征解旋酶-核酸酶 (WRN) 抑制剂，对 WRN、BLM 和 FANCJ 解旋酶的 IC50 分别为 2.3 μM、12.5 μM 和 3.4 μM。

NCGC00029283 is a werner syndrome helicase-nuclease (WRN) helicase inhibitor with IC 50 s of 2.3 μM, 12.5 μM, and 3.4 μM for WRN, BLM and FANCJ helicase, respectively.

NCGC00029283 (0-100 μM; 24-72 h) effectively blocks cell proliferation in U2-OS cells[1].

714240-31-0

C18H12FN3O3

337.30

DMSO:6.3mg/mL (18.7mM),ultrasonic and warming and heat to 60°C
Powder: -20°C for 3 years
In solvent: -80°C for 2 years