Argipressin 是一种具有血管收缩和抗利尿活性的肽激素，可与血管精氨酸加压素受体 V1 结合，在 A7r5 大鼠主动脉平滑肌细胞和新生大鼠心肌细胞中的 Kd 值分别为 1.31 和 1.44 nM。

Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V1, with Kd values of 1.31 and 1.44 nM in A7r5 rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively.

Argipressin stimulates the intracellular release of calcium in A7r5 cells (EC50 = 5 nM)[1].

In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.

113-79-1

C48H69N15O14S2

1144.29

Arg8-vasopressin;AVP;Vasopressin;醋酸精氨酸加压素;精氨加压素

H2O:100 mg/mL (92.23 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years