| CAS NO: | 162641-16-9 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| Cas No. | 162641-16-9 |
| 别名 | 4-(二苯基甲氧基)-1-[3-(2H-四氮唑-5-基)丙基]哌啶 |
| 化学名 | 1-(3-(2H-tetrazol-5-yl)propyl)-4-(benzhydryloxy)piperidine |
| Canonical SMILES | N1(CCCC2=NNN=N2)CCC(CC1)OC(C3=CC=CC=C3)C4=CC=CC=C4 |
| 分子式 | C22H27N5O |
| 分子量 | 377.48 |
| 溶解度 | Methanol: 2.5 mg/ml |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | HQL-79 is a potent, selective and orally active human hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with a Kd of 0.8 μM and an IC50 of 6 μM. Shows no obvious effect on COX-1, COX-2, m-PGES, or L-PGDS[1]. HQL-79 is a competitive inhibitor against substrate PGH2 and a non-competitive one against GSH[1]. References: |
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