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Sodium salicylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sodium salicylate图片
CAS NO:54-21-7
包装与价格:
包装价格(元)
500 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
Salicylic acid sodium salt
2-Hydroxybenzoic acid sodium salt
水杨酸钠
产品介绍
Sodium Salicylate 是一种S6K的抑制剂,可抑制COX-2活性。它还是一种NF-Κb抑制剂,可降低炎症基因的表达,促进老化肌肉的修复。

产品描述

Sodium salicylate, a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.

体外活性

Sodium salicylate acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. Sodium salicylate inhibits the activation of NF-kappa B, and also inhibits NF-kappa B-dependent transcription from the Ig kappa enhancer and the human immunodeficiency virus (HIV) long terminal repeat (LTR) in transfected T cells. [1] Sodium salicylate also induces apoptosis via p38 MAPK and inhibits TNF-induced JNK/stress-activated protein kinase activation. [2]

Cas No.

54-21-7

分子式

C7H5NaO3

分子量

160.104

别名

Salicylic acid sodium salt;2-Hydroxybenzoic acid sodium salt;水杨酸钠

储存和溶解度

DMSO:30 mg/mL (187.4 mM)
Ethanol:<1 mgml
H2O:29 mg/mL (181.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years