Proglumide 是一种非肽的、口服具有活性的胆囊收缩素(CCK)-A/B受体拮抗剂。它能够选择性阻断CCK在中枢神经系统中的作用。它能够抑制胃分泌,具有保护胃十二指肠粘膜的能力,并表现出抗癫痫和抗氧化活性。
产品描述
Proglumide is a cholecystokinin antagonist, which blocks both the CCKA and CCKB subtypes. Proglumide is a drug that exerts an inhibitory effect on gastric secretion and reduces gastrointestinal motility. It is used clinically in the drug therapy of gastrointestinal ulcers.
Cas No.
6620-60-6
分子式
C18H26N2O4
分子量
334.416
别名
Binoside;二丙谷酰胺;Xylamide
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years