DeSmorpholinyl Navitoclax-NH-Me 是一种BCL-xL抑制剂。它和 E3 泛素连接酶的 CRBN 配体可于合成 PROTAC BCL-XL 降解剂 XZ739。

Desmorpholinyl Navitoclax-NH-Me is a Bcl-xL inhibitor. Desmorpholinyl Navitoclax-NH-Me and a CRBN ligand for the E3 ubiquitin ligase can be used in the synthesis of PROTAC BCL-XL degrader XZ739 [1] [2] .

2365172-82-1

C44H51ClF3N5O5S3

918.55

Desmorpholinyl ABT-263-NH-Me;Desmorpholinyl Navitoclax-NH-Me

DMSO:100 mg/mL (108.87 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years