Methyl cinnamate 是花椒的有效成分,也是一种天然香料。它是一种防止食品褐变的酪氨酸酶抑制剂,具有抗菌活性。它通过由CaMKK2-AMPK信号途径介导的机制具有抗脂活性。
产品描述
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.
体外活性
At 1-3000 μmol/L, the E-isomer of methyl cinnamate (E-MC) concentration-dependently relaxed endothelium-intact aortic preparations that had been precontracted with phenylephrine (PHE; 1 μmol/L), with an IC50 value (geometric mean) of 877.6 μmol/L (95% confidence interval (CI) 784.1-982.2 μmol/L). Over the concentration range 1-3000 μmol/L, E-MC relaxed K(+) -induced contractions in mesenteric artery preparations (IC50 314.5 μmol/L; 95% CI 141.9-697.0 μmol/L) with greater potency than in aortic preparations (IC50 1144.7 μmol/L; 95% CI 823.2-1591.9 μmol/L).
Cas No.
103-26-4
分子式
C10H10O2
分子量
162.188
储存和溶解度
H2O:Insoluble
DMSO:30 mg/mL (184.97 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years