Phenyl-β-D-glucopyraNOSide 是黄柏的一种成分，具有抗癌和抗炎活性。

Phenyl-β-D-glucopyranoside is a component of Phellodendron amurense with anti-cancer and anti-inflammatory activities.

Phenyl-β-D-Glucopyranoside Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated RAW 264.7 Cells. Phenyl-β-D-glucopyranoside not only inhibited nitric oxide (NO) production but also significantly inhibited the expression of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) without inducing cytotoxicity. Phenyl-β-D-glucopyranoside also attenuated proinflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and other inflammation-related genes, such as IL-6 in a concentration-dependent manner. Furthermore, phenyl-β-D-glucopyranoside abolished increased adhesion, ninjurin 1 (Ninj1) expression, and matrix metalloproteinase (MMP) activity induced by endotoxin treatment. Finally, phenyl-β-D-glucopyranoside inhibited the nuclear translocation of nuclear factor-κB (NF-κB), which is one of the most important transcription factors involved in the inflammatory process.

1464-44-4

C12H16O6

256.25

PHENYL-B-D-GLUCOPYRANOSIDE;苯基-BETA-葡萄糖吡喃糖苷

DMSO:60 mg/ml (234.15 mM)
H2O:soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years