Dehydrodiisoeugenol 是从Myristica fragrans Houtt中分离得到的天然产物，具有抗炎和抗菌作用。它抑制 LPS 刺激的小鼠巨噬细胞中NF-Κb活化和环氧合酶 (COX)-2 基因的表达。

1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated with LPS. (2). Dehydrodiisoeugenol inhibited LPS-stimulated phosphorylation-dependent proteolysis of inhibitor κB-α and transcriptional activity of NF-κB in the cells.

2680-81-1

C20H22O4

326.392

去氢二异丁香酚;脱氢二异丁香酚

DMSO:59 mg/mL(180.8 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years