7,8-Dihydroxy-4-methylcoumarin 是一种合成 4-甲基香豆素衍生物的前体。它对几种肿瘤细胞株具有选择性的抗增殖和诱导凋亡的作用。它能够清除自由基,显著抑制膜脂过氧化。
产品描述
1. 4-Methyldaphnetin is a potent inhibitor (low micromolar) of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals, but may be pro-oxidant (enhancing generation of hydroxyl radicals) in the presence of free iron ions.2. 4-Methyldaphnetin inhibits the proinflammatory 5-lipoxygenase enzyme at micromolar concentrations.
Cas No.
2107-77-9
分子式
C10H8O4
分子量
192.17
别名
DHMC;4-甲基瑞香素;7,8-Dihydroxy-4-methylcoumarin;7,8-二羟基-4-甲基香豆素
储存和溶解度
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble
DMSO:35 mg/mL(182.1 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years