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Atezolizumab
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1380723-44-3
包装:5 mg
市场价:5415元

产品名称
阿特珠单抗
阿特朱单抗
产品介绍
Atezolizumab 是一种人源化单克隆抗体 IgG1,能抵抗程序性死亡因子配体1 ,可用于癌症研究。

产品描述

Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1.

细胞实验

Objective: Determine the binding of [111In]PD-L1-mAb to tumor cell lines. Cells: NCI-H2444(Lung Cancer cell line), MDAMB231(Breast Cancer cell line),etc. Concentrations: 1 μCi/100μl. Incubation Time: 1 h. Method: Incubating 1 μCi of [111In]PD-L1-mAb with 1×106cells (in triplicate for each cell line) for 1h at 37°C. PD-L1 blocking was performed by adding a 10-fold molar equivalent excess of the non-labeled mAb. After incubation, cells were washed three times with cold PBS prior to counting on an automated gamma counter.

Cas No.

1380723-44-3

分子量

145 kDa

别名

阿特珠单抗;阿特朱单抗