Lisaftoclax 是一种双重 BCL-2 和 BCL-xl 抑制剂（IC50：2 nM 和 5.9 nM），具有抗肿瘤活性。

Lisaftoclax is a dual Bcl-2 and Bcl-xl inhibitor (IC50: 2 nM and 5.9 nM) with antitumor activity.

Lisaftoclax shows IC50s of 5.5 nM and 6.4 nM in Bcl-2 dependent RS4 11 cells and Bcl-xl dependent Molm 13 cells[1].

2180923-05-9

C45H48ClN7O8S

882.42

Bcl-2/Bcl-xl inhibitor 1;APG-2575

DMSO:225mg/mL (255mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years