Neogambogic acid, an active ingredient ingarcinia, inducesapoptosisand has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)^[1][2].

Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC₅₀between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro^[1].

Neogambogic acid arrests A549-induced tumor growth in nude mice^[1].

646.77

C₃₈H₄₆O₉

93772-31-7

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