CAS NO: | 2454133-88-9 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Antitumor agent-70 (compound 8b) has anti-tumor activity and can induce cellapoptosis. Antitumor agent-70 inhibits multiple myeloma with anIC50value of 0.12 μM. Antitumor agent-70 is a potential multi-targeted kinase inhibitor especially forc-Kit[1]. | ||||||||||||||||||||||||
体外研究 (In Vitro) | Antitumor agent-70 (compound 8b) (0-50 μM, 24 hours) has excellent anti-tumor proliferative activity, especially against multiple myeloma cell RPMI8226[1].Antitumor agent-70 (compound 8b) (0-0.2 μM, 24 hours) arrests the cell cycle in G0/G1 phase[1].Antitumor agent-70 (compound 8b) (0-0.2 μM, 24 hours) can induce apoptosis to inhibit cell proliferation by promoting ROS release cells[1]. Cell Proliferation Assay[1]
Cell Cycle Analysis[1]
Apoptosis Analysis[1]
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分子量 | 358.39 | ||||||||||||||||||||||||
Formula | C21H18N4O2 | ||||||||||||||||||||||||
CAS 号 | 2454133-88-9 | ||||||||||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |