您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > AGN 210676
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
AGN 210676
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AGN 210676图片
CAS NO:910562-15-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
Simenepag
产品介绍
AGN 210676 是一种有效的选择性前列腺素EP2激动剂,EC50为 5 nM。详细信息请参考专利文献 US20070203222A1 中的化合物 example 23。
生物活性

AGN 210676 is a selective prostaglandinEP2agonist extracted from patent US20070203222A1, Compound example 23, has anEC50of 5 nM.

IC50& Target

EC50: 5 nM (EP23A receptor), 7749 nM (hDP receptor)[1]

体外研究
(In Vitro)

AGN 210676 (Compound 23) also is a less potent agonist for recombinant human prostaglandin receptors hEP3A and hDP with EC50s of 153 nM and 7749 nM, respectively. AGN 210676 is useful for the treatment of glaucoma, ocular hypertension, inflammatory bowel disease, and the other diseases or conditions disclosed herein[1].

分子量

431.55

Formula

C23H29NO5S

CAS 号

910562-15-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.