Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifyingLPS(HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality^[1].

Endotoxin inhibitor (i.p., 0.5 mg/kg) 可以显著减弱热暴露引起的 IL-1β、COX-2、IκB-β 和 LPS 活性的 mRNA 增加，以及在老年大鼠中热暴露引起的低体温和血浆 ACTH 和儿茶酚胺反应作用^[1]。

1224.58

C₅₅H₉₇N₁₅O₁₂S₂

147396-10-9

KTKCKFLKKC (Disulfide bridge: Cys4-Cys10)

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.