Cyanine5 alkyne (Alkyne-Cy5) is afluorescent dyeused to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrialOXPHOSinhibitor to inhibit the growth ofcancer stem cells(CSC)^[1][2].

Cyanine5 alkyne (Alkyne-Cy5) (1-1000 nM) significantly inhibits 3D mammosphere formation in MCF7 cells between 500 nM and 1000 nM and can act as a mitochondrial oxidative phosphorylation (OXPHOS) inhibitor, inducing glycolysis to compensate for mitochondrial ATP depletion^[2].

556.18

C₃₅H₄₂ClN₃O

1223357-57-0

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.