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Methyltetrazine-amido-N-bis(PEG4-acid)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Methyltetrazine-amido-N-bis(PEG4-acid)图片
CAS NO:2639395-39-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Methyltetrazine-amido-N-bis(PEG4-acid) 是一种含有叠氮基团的点化学试剂。Methyltetrazine-amido-N-bis(PEG4-acid) 是一种 PEG 衍生物,包含一个甲基四氮基和两个酸基。该试剂可与含 TCO 的化合物反应形成稳定的共价键,无需 Cu 的催化和高温。TCO 与四嗪的 Diels-Alder 环加成反应是最快的生物正交反应,具有优异的选择性。末端羧酸可以在激活剂 (如 EDC 或 HATU) 的存在下与伯胺基团反应,形成稳定的酰胺键。PEG 连接剂增加了化合物的水溶性。试剂级,仅供研究用。
生物活性

Methyltetrazine-amido-N-bis(PEG4-acid) is aclick chemistryreagent containing an azide group. Methyltetrazine-amido-N-bis(PEG4-acid) is a PEG derivative that contains a methyltetrazine group and two acid groups. This reagent can react with TCO-containing compounds to form a stable covalent bond without the catalysis of Cu or elevated temperatures. The inverse-electron demand Diels-Alder cycloaddition reaction of TCO with tetrazines is the fastest bioorthogonal reaction with exceptional selectivity. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. PEG linker increases the water solubility of the compound. Reagent grade, for research use only[1].

分子量

725.78

Formula

C33H51N5O13

CAS 号

2639395-39-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.