CAS NO: | 1808948-28-8 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | (2S,3R)-LP99 is a potent and selectiveBRD7andBRD9inhibitor with anKDof 99 nM forBRD9. (2S,3R)-LP99 inhibits the association ofBRD7andBRD9to acetylated histones in vitro and in cells. (2S,3R)-LP99 demonstrates that BRD7/9 plays a role in regulating pro-inflammatory cytokine secretion[1]. | ||
IC50& Target[1] |
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体外研究 (In Vitro) | (2S,3R)-LP99 (compound 60) (0-100 μM) inhibits the expression of IL6 in LPS-stimulated (100 ng/mL) THP-1 cells[1]. | ||
分子量 | 516.05 | ||
Formula | C26H30ClN3O4S | ||
CAS 号 | 1808948-28-8 | ||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |