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Zy3 carboxylic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Zy3 carboxylic acid图片
CAS NO:146368-13-0
包装与价格:
包装价格(元)
10mM (in 1mL Water)电议
5mg电议

产品介绍
Cy3 (Sulfo-Cyanine3) 是蛋白质和核酸的橙色荧光标记 (Λex=554, Λem=568)。
Cas No.146368-13-0
别名磺基-CY3羧酸,Sulfo-Cyanine3
Canonical SMILESCC(/C(N1CCCCCC(O)=O)=C\C=C\C2=[N+](CC)C(C=CC(S([O-])(=O)=O)=C3)=C3C2(C)C)(C)C4=C1C=CC(S(=O)(O)=O)=C4
分子式C31H38N2O8S2
分子量630.77
溶解度Water : 16 mg/mL (25.37 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Zy3 carboxylic acid (Compound 7c) is a novel cyanine dyes with vinylsulfone group for labeling biomolecules with maximum wavelength (λabs) and emission maximum wavelength (λem) of 549 nm and 566 nm, respectively.

To ensure labeling efficiency, whether there is any effect from the difference in the length of the spacer is determine. For the 550 nm range, 7a, Zy3 carboxylic acid (Compound 7c), 7f, and 7g having five, six, eight, and eight carbon atoms in the spacer, respectively, are chosen. For the spacer-dependent reactivity test, dyes with the highest extinction coefficients (7g, 7l, and 7n) and those with ethyl groups as R on indole (7a, Zy3 carboxylic acid, 7f, and 7i) are selected. As a result, dyes with longer spacers are observed to have aster binding affinity to BSA. Among 7a, Zy3 carboxylic acid, 7f, and 7g, with the same absorption wavelength at ~550 nm (m=1)[1].

[1]. Park JW, et al. Novel cyanine dyes with vinylsulfone group for labeling biomolecules. Bioconjug Chem. 2012 Mar 21;23(3):350-62.