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Timolol hemihydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Timolol hemihydrate图片
CAS NO:91524-16-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Timolol (hemihydrate) 是一种β受体阻滞剂,可用于局部和全身给药。Timolol (hemihydrate) 用于降低开角型青光眼和高眼压,还具有保护心脏的作用。
生物活性

Timolol (hemihydrate) is aβ-blockeravailable for both topical and systemic administration. Timolol (hemihydrate) is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension and Timolol (hemihydrate) also has cardioprotective effect[1][2].

体外研究
(In Vitro)

Timolol (hemihydrate) can significantly prevent the increased lipid peroxidation level of the heart from diabetic rats. Timolol (hemihydrate) can induce a well-balanced ratio between oxidative stress and antioxidant defense system in the diabetic animals, can have an important cardioprotection against diabetes-induced ERS and associated apoptotic effects[3].

体内研究
(In Vivo)

Timolol (hemihydrate) (5 mg/kg daily for 12-week) has a cardioprotective effect via inhibition of ERS response in diabetic rats[3].

Animal Model:Male Wistar rats[3].
Dosage:5 mg/kg
Administration:Timolol (5 mg/kg daily for 12-week)
Result:Showed cardioprotective effect.
Clinical Trial
分子量

325.43

Formula

C13H24N4O3S.1/2H3O

CAS 号

91524-16-2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.