您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Wilforlide A
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Wilforlide A
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Wilforlide A图片
CAS NO:84104-71-2
包装:20mg
市场价:3119元

产品介绍
Wilforlide A 是一种从雷公藤中分离出来的生物活性三萜。
Cas No.84104-71-2
别名雷公藤内酯甲; Regelide; Abruslactone A
化学名(2S,5S,5aR,7aS,7bR,9aR,11S,13aR,13bR,15bS)-11-hydroxy-2,5a,7a,7b,10,10,13a-heptamethyl-1,5,5a,6,7,7a,7b,8,9,9a,10,11,12,13,13a,13b,14,15b-octadecahydro-2,5-methanochryseno[2,1-c]oxepin-3(2H)-one
Canonical SMILESO[C@H]1CC[C@@]2(C)[C@](CC[C@]3(C)[C@]2([H])CC=C4[C@@]3(C)CC[C@]5(C)[C@@]4([H])C[C@@]6(C)C[C@@H]5OC6=O)([H])C1(C)C
分子式C30H46O3
分子量454.68
溶解度<4.55mg/mL in EtOH, Limited solubility in DMSO
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Wilforlide A is a natural product, separated from the ethanolic extract of tripterygium wilfordii. IC50 value:Target:In vitro:In vivo: Carrageenan-induced rat pedal swelling, tampon-induced rat granulation, and mice ear inhibition rate of swelling trail results show that high-dose wilforlide A has obvious anti-inflammatory effect, but has no significant immune suppressive activity [1].

References:
[1]. Mei Xue, et al. Comparative study on the anti-inflammatory and immune suppressive effect of Wilforlide A. Fitoterapia Volume 81, Issue 8, December 2010, Pages 1109–1112
[2]. HU Jian-lin, et al. Determination of Wilforlide A in Tripterygium hypoglaucum (Levl.) Hutch by HPLC. Journal of Kunming Medical College, 2010-07