Liriodenine (Spermatheridine; VLT045) is an aporphine alkaloid isolated from the plant Mitrephora sirikitiae and has anti-cancer activities^[1]. Liriodenine induces cellapoptosis, activates the intrinsic pathway by induction of caspase-3 and caspase-9^[2].

Liriodenine is against P-388, KB, HT-29, MCF-7, A549, ASK and Hek-293 cells with IC₅₀values of 9.60 μM, 11.02 μM, 10.62 μM, 9.20 μM and 8.07μM, respectively.

275.26

C₁₇H₉NO₃

475-75-2

• Alkaloids
• Pyridine Alkaloids

• Plants
• Magnoliaceae
• Liriodendron chinense(Hemsl.) Sarg.

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.