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DETA NONOate
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
DETA NONOate图片
CAS NO:146724-94-9
包装与价格：
包装价格(元)
10mg电议
50mg电议
100mg电议
500mg电议

产品介绍
DETA NONOate (NOC-18) 是一种外源性一氧化氮 (NO) 供体。
Cas No.146724-94-9
别名Diethylamine NONOate; NOC-18
化学名(Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate
Canonical SMILES[NH3+]CCN(N(N=O)[O-])CCN
分子式C4H13N5O2
分子量163.2
溶解度aqueous buffers: >100 mg/ml
储存条件Store at -80℃, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

DETA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 20 hours and 56 hours at 37℃ and 22-25℃, pH 7.4, respectively, to liberate 2 moles of NO per mole of parent compound.[1],[2]

Reference:

[1]. Hrabie, J.A., Klose, J.R., Wink, D.A., et al. New nitric oxide-releasing zwitterions derived from polyamines The Journal of Organic Chemistry 58, 1472-1476 (1993).
[2]. Keefer, L.K., Nims, R.W., Davies, K.M., et al. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: Convenient nitric oxide dosage forms Methods in Enzymology 268, 281-293 (1996).