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GSK-650394
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GSK-650394图片
CAS NO:890842-28-1
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
GSK 650394, GSK650394
产品介绍

生物活性

GSK 650394是一种糖皮质激素和血清调节激酶1(SGK1)抑制剂,对LNCaP前列腺癌细胞系表现出抗增殖特性。

靶点信息

SGK1SGK2
62 nM103 nM

化学数据

目录号A13309
作用机制Inhibitor (抑制剂)
M. Wt382.45
FormulaC25H22N2O2
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.890842-28-1
SynonymsGSK 650394, GSK650394
SMILESC1CCC(C1)C2=C(C=CC(=C2)C3=CNC4=NC=C(C=C34)C5=CC=CC=C5)C(=O)O

溶解度

In vitroDMSO72 mg/mL (188.25 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM26.15 mL130.74 mL261.47 mL
0.5 mM5.23 mL26.15 mL52.29 mL
1 mM2.61 mL13.07 mL26.15 mL
5 mM0.52 mL2.61 mL5.23 mL

*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.