Amphotericin B methyl ester

立即咨询

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

36148-89-7

包装与价格：

包装	价格(元)
50mg	电议
100mg	电议

产品介绍

Amphotericin B methyl ester 是多烯类抗生素 Amphotericin B (A634250) 的甲酯衍生物。Amphotericin B methyl ester 是胆固醇结合物，具有显著的抗真菌活性。Amphotericin B methyl ester 干扰 HIV-1 颗粒的产生，抑制 HIV-1 的复制。

生物活性

Amphotericin B methyl ester is the methyl ester derivative of the polyeneantibioticAmphotericin B (A634250). Amphotericin B methyl ester is the cholesterol-binding compound possesses significant antifungal activity. Amphotericin B methyl ester disruptsHIV-1particle production and potently inhibitsHIV-1replication^[1]^[2].

体外研究
(In Vitro)

Amphotericin B methyl ester inhibits HIV-1 particle production with no significant effect on Gag binding to the plasma membrane, Gag association with lipid rafts, or Gag multimerization^[1].

分子量

938.11

Formula

C₄₈H₇₅NO₁₇

CAS 号

36148-89-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

溶解性数据

In Vitro:

DMSO : 50 mg/mL(53.30 mM;Need ultrasonic)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	1.0660 mL	5.3299 mL	10.6597 mL
5 mM	0.2132 mL	1.0660 mL	2.1319 mL
10 mM	0.1066 mL	0.5330 mL	1.0660 mL