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D-3263
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
D-3263图片
CAS NO:947257-66-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
D-3263 是一种有效的TRPM8激动剂,具有抗肿瘤活性。
生物活性

D-3263 is an agonist of transient receptor potential melastatin member 8 (TRPM8) with potential antineoplastic activity.

体外研究
(In Vitro)

D-3263 induces calcium flux and cell death in in vitro cells expressing TRPM8[1].

体内研究
(In Vivo)

D-3263 (50 or 100 mg/kg/d) alone or with Finasteride (10 mg/kg/d) results in reduction in prostate hyperplasia of rats with evidence of a dose response. The highest dose of the TRPM8 agonist D-3263, given in combination with Finasteride, results in lower prostate weights than the highest dose of D-3263 or Finasteride given alone, suggesting a potential additive effect[1].

Clinical Trial
分子量

373.49

Formula

C21H31N3O3

CAS 号

947257-66-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.