您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Ranolazine-d5
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Ranolazine-d5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Ranolazine-d5图片
CAS NO:1092804-87-9
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
CVT 303-d5
RS 43285-003-d5
产品介绍
Ranolazine-d5 (CVT 303-d5) 是 Ranolazine 的氘代物。Ranolazine (CVT 303) 是一种抗心绞痛和抗缺血剂,可通过抑制内向钠电流的后期作用 (对INaIKrIC50值分别为 6 μM 和 12 μM) 来发挥功效,而不会影响心率或血压。Ranolazine 还是脂肪酸氧化 (FAO) 的部分抑制剂。具有抗心绞痛作用。
生物活性

Ranolazine-d5 (CVT 303-d5) is the deuterium labeled Ranolazine. Ranolazine (CVT 303) is an anti-angina drug that achieves its effects by inhibiting the late phase of inwardsodiumcurrent (INaandIKrwithIC50values of 6 μM and 12 μM, respectively) without affecting heart rate or blood pressure (BP)[1][2]. Ranolazine is also a partialfatty acid oxidation (FAO)inhibitor[3]. Antianginal agent.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

432.57

Formula

C24H28D5N3O4

CAS 号

1092804-87-9

中文名称

雷诺嗪 d5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.