CAS NO: | 59878-63-6 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties. |
体外研究 (In Vitro) | The main urine metabolites of racemic zopiclone are the less active eszopiclone-N-oxide (RP 29753) and the inactive Norzopiclone (N-desmethyleszopiclone, RP 32273)[1]. Zopiclone has two major metabolites, N-oxideZopiclone and Norzopiclone (N-desmethyl-Zopiclone). N-oxideZopiclone has a hypnotic activity lower than the parent Zopiclone, whereas Norzopiclone (N-desmethyl-Zopiclone) lacks hypnotic effect, but has some anxiolytic properties[3]. |
体内研究 (In Vivo) | A demethylation metabolic pathway produces Norzopiclone (N-desmethylzopiclone), a metabolite which reportedly accounts for 15% of an oral dose of racemic Zopiclone, and which is also reportedly inactive[2]. N-oxide-Zopiclone has a similar t1/2compared to parent Zopiclone, while the t1/2of Norzopiclone (N-desmethyl-Zopiclone) ranges from 7 to 11 h[3]. |
分子量 | 374.78 |
Formula | C16H15ClN6O3 |
CAS 号 | 59878-63-6 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |