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Norzopiclone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Norzopiclone图片
CAS NO:59878-63-6
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
N-Desmethyl zopiclone
RP 32273
产品介绍
Norzopiclone 是 Zopiclone 的无活性代谢物。Norzopiclone 具有一定的抗焦虑特性。
生物活性

Norzopiclone is the inactive metabolite of Zopiclone. Norzopiclone has some anxiolytic properties.

体外研究
(In Vitro)

The main urine metabolites of racemic zopiclone are the less active eszopiclone-N-oxide (RP 29753) and the inactive Norzopiclone (N-desmethyleszopiclone, RP 32273)[1]. Zopiclone has two major metabolites, N-oxideZopiclone and Norzopiclone (N-desmethyl-Zopiclone). N-oxideZopiclone has a hypnotic activity lower than the parent Zopiclone, whereas Norzopiclone (N-desmethyl-Zopiclone) lacks hypnotic effect, but has some anxiolytic properties[3].

体内研究
(In Vivo)

A demethylation metabolic pathway produces Norzopiclone (N-desmethylzopiclone), a metabolite which reportedly accounts for 15% of an oral dose of racemic Zopiclone, and which is also reportedly inactive[2]. N-oxide-Zopiclone has a similar t1/2compared to parent Zopiclone, while the t1/2of Norzopiclone (N-desmethyl-Zopiclone) ranges from 7 to 11 h[3].

分子量

374.78

Formula

C16H15ClN6O3

CAS 号

59878-63-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.