CAS NO: | 126050-12-2 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | MEN 10207 is a selectiveNK-2 tachykinin receptor(Neurokinin Receptor) antagonist. MEN 10207 has pA2values of 5.2, 7.9 and 4.9 in three monoreceptor in vitro assays for NK-1, NK-2 and NK-3 tachykinin receptors, respectively[1][2]. | ||||||||
IC50& Target[2] |
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体外研究 (In Vitro) | In competitive radioligand binding assays, MEN 10207 (the IC50ranges of 21-54 nM) has high affinity in bovine stomach membranes and SKLKB82#3 cells, a murine fibroblast cell line transfected with a cDNA encoding for the bovine NK2 receptor[3]. | ||||||||
体内研究 (In Vivo) | but not Substance P in a dose-dependent manner. And MEN 10207 also effectively blocks the long-term reflex facilitation to the gastrocnemius nerve stimulation[1].
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分子量 | 1109.24 | ||||||||
Formula | C57H68N14O10 | ||||||||
CAS 号 | 126050-12-2 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |