您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Pranlukast-d4
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Pranlukast-d4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pranlukast-d4图片
CAS NO:2713172-43-9
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
ONO-1078-d4
产品介绍
Pranlukast-d4 是 Pranlukast 氘代物。Pranlukast 是一种高效的竞争性的选择性leukotriene拮抗剂。Pranlukast 抑制 [3H]LTE4,[3H]LTD4和 [3H]LTC4与肺膜结合,Ki分别为 0.63±0.11,0.99±0.19 和 5640±680 nM。
生物活性

Pranlukast-d4 is deuterium labeled Pranlukast. Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotrienes. Pranlukast inhibits [3H]LTE4, [3H]LTD4, and [3H]LTC4 bindings to lung membranes with Kis of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

485.53

Formula

C27H19D4N5O4

CAS 号

2713172-43-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.