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Dexpramipexole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Dexpramipexole图片
CAS NO:104632-28-2
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
右旋普拉克索
(R)-Pramipexole
R-(+)-Pramipexole
KNS-760704
产品介绍
Dexpramipexole(KNS-760704)也叫R-(+)-Pramipexole,是神经保护剂,是弱的非麦角类多巴胺受体激动剂。
生物活性

Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. IC50 Value: Target:Dopamine ReceptorDexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrialreactive oxygen species(ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, Dexpramipexole has much lower dopamine agonist activity.

Clinical Trial
分子量

211.33

Formula

C10H17N3S

CAS 号

104632-28-2

中文名称

右旋普拉克索

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.