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Trimethobenzamide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Trimethobenzamide图片
CAS NO:138-56-7
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
Ro 2-9578 free base
产品介绍
Trimethobenzamide (Ro 2-9578 free base) 是多巴胺D2受体阻断剂,可用作预防恶心和呕吐的止吐剂。
生物活性

Trimethobenzamide (Ro 2-9578 free base) is a blocker of theD2receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting[1].

IC50& Target

D2receptor[1]

体外研究
(In Vitro)

Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center[1].

体内研究
(In Vivo)

The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration[1].

Clinical Trial
分子量

388.46

Formula

C21H28N2O5

CAS 号

138-56-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.