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7-keto-deoxycholic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-keto-deoxycholic acid图片
CAS NO:911-40-0
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品名称
7-酮-3α,12-α-二羟基胆酸
产品介绍
7-keto-lithocholic acid 是胆酸在Clostridium absonum中的代谢产物。7-keto-lithocholic acid 也可由乳酸杆菌和双歧杆菌在特定条件下也可转化得到。
生物活性

7-keto-lithocholic acid is a metabolite of bile acids inClostridium absonum. 7-keto-lithocholic acid is also converted fromLactobacillusandBifidobacteriumwith specific condition[1][2].

体外研究
(In Vitro)

7-keto-lithocholic acid shows an increasing bioconversion rate with addition of an equimolar concentration of deoxycholic acid (which itself is not metabolized)[1].
7-keto-lithocholic acid is induced by deoxycholic acid and then it's metabolized[1].
E.lentum-like c-25 converts 81.7% of 2 mM cholic acid to deoxycholic acid and 3.7% to 7-keto-deoxycholic acid under anaerobic incubation[2].
E.lentum-like c-25 converts 91.5% of 150 mg/mL cholic acid to deoxycholic acid and 1.1% to 7-keto-deoxycholic acid under anaerobic incubation[2].

分子量

406.56

性状

Solid

Formula

C24H38O5

CAS 号

911-40-0

中文名称

7-酮-3α,12-α-二羟基胆酸

结构分类
  • Ketones, Aldehydes, Acids
来源

human

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
In Vitro: 

DMSO : 100 mg/mL(245.97 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM2.4597 mL12.2983 mL24.5966 mL
5 mM0.4919 mL2.4597 mL4.9193 mL
10 mM0.2460 mL1.2298 mL2.4597 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。